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2026-05-19 08:06:20

Ceramic Hydroxyapatite in Biomolecule Purification: Comparison with Ion Exchange and Affinity Chromatography

Ceramic hydroxyapatite (CHT) chromatography is a mixed-mode separation technique used in biomolecule purification, including proteins, antibodies, and nucleic acids. It is based on calcium phosphate interactions, which enable both ionic and specific binding mechanisms. Because of this dual interaction behavior, CHT is often positioned between ion exchange chromatography and affinity...

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