Advantages Over Antibody-Based Targeting

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Question: What are the primary advantages of using aptamers instead of antibodies for tumor cell engineering? Answer: Compared to traditional antibodies, aptamers offer smaller molecular size, better tissue penetration, and lower production costs through chemical synthesis. Furthermore, custom target-specific aptamer design allows for high stability under various physiological conditions and the ability to be easily modified with fluorophores or drug payloads without losing binding affinity, making them ideal for complex immunotherapy applications.

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