The Raptors lost Brandon Ingram early on Wednesday night with a right heel injury, something that could make a significant impact as they enter a must-win game later this week in Toronto.Ingram left the teams 125-120 loss to the Cleveland Cavaliers early on Wednesday. That gave Cleveland a 3-2 lead in the series and put them just a win away from making it to their third straight Eastern Conference semifinals.Ingram left the game near the midway point of the second quarter losing the ball on a jumpshot near the wing. It didnt appear that anything happened in the moment, but he pulled up limping after Evan Mobley, who got his hand on Ingrams shot attempt, was fouled at the other end.Ingram checked himself out of the game and limped off to the locker room at Rocket Arena. He did not return, and the team quickly ruled him out with a right heel injury.Brandon Ingram heads to the locker room with 7:32 minutes remaining in the 2nd quarter due to an injury - did not return since. pic.twitter.com/YQICFRlUVm MrBuckBuck (@MrBuckBuckNBA) April 30, 2026Ingram had just one point and two assists in 11 minutes when he went down. He entered Wednesday averaging 14.8 points and 3.8 rebounds per game so far in the series with Cleveland.Even though the Cavaliers managed just a single point in the final three minutes of the game, they held on to grab the five-point win. James Harden led the Cavaliers with 23 points, nine rebounds and five assists. Mobley had 23 points and nine rebounds, too, and Donovan Mitchell added 19 points. They shot 50% from behind the arc, too.RJ Barrett led Toronto with 25 points and 12 rebounds, and was one of six players to hit double figures. JaKobe Walter added 20 points on six 3-pointers, and Scottie Barnes finished just shy of a triple-double with 17 points, 11 assists and eight rebounds.The Cavaliers, now a perfect 10-0 against the Raptors in the postseason at home, are a near-undefeated 10-1 in the playoffs when leading a series 3-2. The Raptors, on the other hand, are 0-5 when trailing 3-2.Game 6 of the series is set for Friday night at Scotiabank Arena.This post will be updated with more information shortly.