ANAHEIM, Calif. (AP) Jose Siri hit a game-winning single in the 10th inning, Mike Trout and Logan OHoppe homered, and the Los Angeles Angels beat the Houston Astros 3-2 on Wednesday night. Angels starter Reid Detmers retired his first 15 batters before Shay Whitcomb homered leading off the sixth. Chase Silseth replaced Detmers to begin the eighth and gave up a leadoff homer to Cam Smith that tied it 2-all. Houston nearly took the lead in the ninth. Yordan Alvarez singled with two outs and Christian Walker followed with a double that appeared to score Alvarez. But the Angels challenged the safe call at home plate and it was overturned following a replay review.Bryan Abreu (2-3) came on for the Astros in the 10th and pinch-hitter Donovan Walton hit a leadoff single that moved automatic runner Nick Madrigal from second base to third. Siri, facing one of his former teams, then hit an 0-2 pitch to left field to drive in Madrigal. Ryan Zeferjahn (3-3) worked a scoreless inning for the win. Trout launched his 15th homer to open the scoring in the first, and O'Hoppe's drive with two outs in the fifth made it 2-0. Peter Lambert allowed two runs and five hits with six strikeouts in 6 1/3 innings for Houston. Detmers permitted only one hit over seven innings. He struck out nine and walked none. The left-hander is third in the American League with 97 strikeouts and has given up three or fewer earned runs in eight of his last nine starts.Alvarez extended his on-base streak to 17 games.Up nextHouston begins a three-game series at Kansas City on Friday night. Los Angeles hosts Tampa Bay in the opener of a three-game set Friday. ___AP MLB: https://apnews.com/hub/MLB